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Amy Orsborn

  • Clare Booth Luce Assistant Professor

Dr. Amy Orsborn joined UW in 2018 as a Clare Boothe Luce Assistant Professor in Electrical & Computer Engineering and Bioengineering. She works at the intersection of engineering and neuroscience to develop therapeutic neural interfaces. She completed her Ph.D. at the UC Berkeley/UCSF Joint Graduate Program in Bioengineering developing co-adaptive strategies for brain-machine interfaces where machine-learning and neural adaptation collaborate to improve system performance. In her postdoctoral training at NYU’s Center for Neural Science, she developed novel neural implants for multi-scale, multi-modal interrogation and monitoring of neural circuits in non-human primates. These implants enable new ways to study neural mechanisms of learning in large-scale networks. Her work has been supported by NSF Graduate Research Fellowship, a pre-doctoral award from the American Heart Association, and a L’Oreal USA for Women in Science postdoctoral award.

Dr. Orsborn’s lab Her explores neural interfaces as adaptive closed-loop systems that engage neural plasticity and adaptation. She uses engineering approaches to leverage neural adaptation for system performance, and uses neural interfaces as a tool to study neural mechanisms of learning in circuits. The lab also specializes in system integration for advancing neurotechnologies to study neural circuits in awake primates for basic science and towards human translation.

Research Interests

  • Brain-machine interfaces
  • Multi-learner adaptive systems
  • Computation in neural networksmulti-scale, multi-modal and large-scale
  • Neural recording technologies
  • System integration for advancing neurotechnologies
  • Motor learning and motor control

Representative publications

  • M. Shanechi*, A. L. Orsborn* (equal contribution), H.G. Moorman*, S.
    Gowda*, and J.M. Carmena (2017). Rapid control and feedback rates enhance
    neuroprosthetic control. Nature Communications, 8:13825,
    doi:10.1038/ncomms13825
  • A.L. Orsborn and B. Pesaran (2017) Parsing learning in networks using
    brain-machine interfaces, Current Opinions in Neurobiology, 46:76-83, doi:
    10.1016/j.conb.2017.08.002
  • M. Shanechi , A.L. Orsborn* (equal contribution), and J.M. Carmena
    (2016). Robust brain-machine interface design using optimal feedback
    control modeling and adaptive point process filtering. PLoS Computational
    Biology 12(4):e1004730. doi:10.1371/journal.pcbi.1004730 (F1000 recommended)
  • A.L. Orsborn, H.G. Moorman, S.A. Overduin, M. M. Shanechi, D.
    Dimitrov, and J.M. Carmena (2014) Closed-loop decoder adaptation shapes
    neural plasticity for skillful neuroprosthetic control, Neuron 82, pp.
    1380-1393. (journal cover article)
  • A.L. Orsborn, S. Dangi, H.G. Moorman, and J.M. Carmena (2012)
    Closed-loop decoder adaptation on intermediate time-scales facilitates
    rapid BMI performance improvements independent of decoder initialization
    conditions. IEEE Transactions on Neural Systems and Rehabilitation
    Engineering, 20(4), pp. 468 – 477.
Amy Orsborn Headshot
Phone206-616-2049
aorsborn@uw.edu
Web PageClick Here
Mail
M430 EEB

Research Areas

Education

  • Postdoctoral Researcher, 2014-2018
    Pesaran Lab, Center for Neural Science, New York University
  • Ph.D. Bioengineering
    University of California, Berkeley/University of California, San Francisco, Joint Graduate Program in Bioengineering, 2013
  • B.S. Engineering Physics, 2007
    Case Western Reserve University